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35

抑制剂 & 化合物

23

天然产物

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Cat. No. Product Name Target Signaling Pathways
T0712 Suloctidil

ATPase; Platelet aggregation Membrane transporter/Ion channel; Others
Suloctidil 是一种外周血管扩张剂,作用于大鼠脑突触, 影响Na+/ K+ ATP 酶活性和膜流动性,可治疗痴呆和血栓形成病症。
T6443 Chloroprocaine hydrochloride

盐酸氯普鲁卡因,Chloroprocaine HCl

ATPase; Others Membrane transporter/Ion channel; Others
Chloroprocaine hydrochloride (Chloroprocaine HCl) 是一种 Na/K-ATPase 活性抑制剂,IC50为 13 mM,可阻断外周神经。
T0490 Chlorpropamide

Diabinese,氯磺丙脲

ATPase; ABC Membrane transporter/Ion channel
Chlorpropamide (Diabinese) 是口服降糖剂,可用于研究非胰岛素依赖型糖尿病。
T6953 Prilocaine

Citanest,丙胺卡因,Propitocaine,NSC 40027

ATPase; Sodium Channel Membrane transporter/Ion channel
Prilocaine (NSC-40027) 是一种氨基酰胺类局部麻醉剂,作用于神经元膜上的钠通道并限制癫痫发作的扩散。它是Na/K-ATPase 抑制剂,具有神经毒性作用。
T0796 Prilocaine hydrochloride

Prilocaine HCl,Propitocaine hydrochloride,Xylonest,盐酸丙胺卡因

ATPase; Sodium Channel Membrane transporter/Ion channel
Prilocaine hydrochloride (Prilocaine HCl) 是一种氨基酰胺类局部麻醉剂,作用于神经元膜上的钠通道并限制癫痫发作的扩散。它是Na/K-ATPase 抑制剂,具有神经毒性作用。
T2176 2,3-Butanedione 2-Monoxime

Diacetyl monoxime,2,3-Butanedione-2-monoxime

Akt Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
2,3-Butanedione 2-Monoxime (Diacetyl monoxime) 是一种肌球蛋白 ATP 酶(myosin ATPase) 抑制剂。它诱导肌质网 Ca2+释放,能够有效抑制骨骼肌和心肌收缩。
T2621 Rostafuroxin

PST 2238

ATPase; RSV Membrane transporter/Ion channel; Microbiology/Virology
Rostafuroxin (PST 2238) 是洋地黄毒苷衍生物,是一种口服有效的 Na+,K+-ATPase 抑制剂,具有抗高血压和抗 RSV 活性,用于研究治疗原发性高血压的试验。
T2189 Sodium orthovanadate

Sodium vanadate,钒酸钠,Trisodium vanadate,Sodium pervanadate

ATPase; Phosphatase Membrane transporter/Ion channel; Metabolism
Sodium orthovanadate 是一种蛋白酪氨酸磷酸酶,碱性磷酸酶和一些ATP 酶的抑制剂,有可能充当磷酸盐类似物。它具有胰岛素样作用、对心室肌的正性肌力作用和其他代谢作用。
T27303 Farglitazar

GI-262570,GI 262570,GI262570

Farglitazar is a PPAR-γ agonist. GI262570 stimulates the ENaC and Na,K-ATPase system resulting in the increasing of water and sodium reabsorption in distal nephron.
T14052 5-IAF

5-Iodoacetamidofluorescein

5-IAF 是吲哚乙酰胺的一种荧光素衍生物,是一种荧光探针,可用来标记蛋白质和其他含有游离硫醇(半胱氨酸侧链)。5-IAF 可标记狗肾脏Na,K-ATP 酶的催化(α)亚单位。
TP1033L Transdermal Peptide Disulfide Acetate

TD 1 (peptide) acetate,Transdermal Peptide Disulfide Acetate (888486-23-5 free base)

ATPase Membrane transporter/Ion channel
Transdermal Peptide acetate(888486-23-5 free base) (TD 1 (peptide) acetate) 是一种 11 个氨基酸的肽,与 Na+/K+-ATPase β 亚基 (ATP1B1) 结合,主要与 ATP1B1 的 C 端相互作用。透皮肽可以增强许多大分子的透皮传递。透皮肽 TD 1 酰胺是一种新型肽,旨在增强透皮药物传递。
T15600 Istaroxime

PST2744

Others Others
Istaroxime is an effective inhibitor of Na+, K+-ATPase (IC50: 0.11 μM).
T15599 Istaroxime hydrochloride

PST2744 hydrochloride

Others Others
Istaroxime hydrochloride is an inhibitor of Na+/K+-ATPase (IC50: 0.11 μM). It also is a sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA 2) activator.
T36060 Digoxigenin Monodigitoxoside

Digoxigenin monodigitoxoside是地高辛的一种Na+/K+ ATPase 抑制剂和强心苷代谢物。
T68916 ASI-254

ASI-254 is an aminosugar cardiac glycoside and an inhibitor of Na+,K+ -ATPase.
T76374 SPAI-1

SPAI-1,特异性单价阳离子ATP酶抑制剂,源自猪十二指肠。能体外抑制Na+,K+-ATP酶和H+,K+-ATP酶,同时刺激Mg2+-ATP酶。
T35923 Caloxin 2A1 TFA

Caloxin 2A1 TFA is a peptide inhibitor specifically targeting the extracellular plasma membrane Ca2+-ATPase (PMCA), without influencing the basal activities of Mg2+-ATPase or Na+-K+-ATPase[1].
T75280 Prilocaine acetate

Prilocaine acetate 是一种氨基酰胺。Prilocaine acetate 是一种Na/K-ATPase 抑制剂。Prilocaine acetate 具有神经毒性作用。
T78564 Depramine

GP 31406

Depramine (GP 31406) 是三环抗抑郁剂,具药理活性。该化合物可抑制乙酰胆碱酯酶、Mg2+-ATPaseNa+/K+ ATPase 活性。
T71806 Tenellin

Tenellin is a fungal metabolite that inhibits Mg2+-, Ca2+-, and Na+/K+-ATPase activities in erythrocytes. Tenellin is cytotoxic to Sf9 and Sf21 insect cells.
T40437 Caloxin 2A1

Caloxin 2A1 is an inhibitor peptide of the plasma membrane Ca 2+-ATPase (PMCA) responsible for extracellular signaling. Importantly, Caloxin 2A1 has no impact on the basal Mg 2+-ATPase or Na+-K+-ATPase activities.
T72812 (R)-Tegoprazan

(R)-Tegoprazan (example 3) 是一种苯并咪唑衍生物,是一种有效的胃H+/K+-ATP 酶抑制剂,对犬肾 Na+/K+-ATPase 的IC50为 98 nM。(R)-Tegoprazan 具有胃肠道疾病研究的潜力。
T60469 Chloroprocaine

Chloroprocaine (2-Chloroprocaine) 是一种有效的NaK-ATPase 酶活性抑制剂(IC50 = 13 mM)。Chloroprocaine 是一种阻滞外周神经的局部麻醉剂。
T37707 14-Anhydrodigitoxigenin

14-Anhydrodigitoxigenin is a cardenolide and a derivative of digitoxin.1 It reduces the activity of guinea pig heart Na+/K+-ATPase by 15% when used at a concentration of 10 μM.2
T37766 Transdermal Peptide (TD 1 (peptide))

Transdermal Peptide is a 11-amino acid peptide, binds to Na+/K+-ATPase beta-subunit (ATP1B1), and enhances the transdermal delivery of many macromolecules. Transdermal Peptide (TD1) binds to ATP1B1, and mainly interacts with the C-terminus of ATP1B1 in yeast and mammalian cells. The interaction affects the expression and localization of ATP1B1 and epidermal structure, but can be antagonized by the exogenous competitor ATP1B1 or be inhibited by ouabain. Inhibition of Transdermal Peptide binding t...
T69975 Istaroxime oxalate

Istaroxime, also known as PST-2744, is a positive inotropic agent that mediates its action through inhibition of sodium/potassium adenosine triphosphatase (Na+/K+ ATPase). Na+/K+ ATPase inhibition increases intracellular sodium levels, which reverses the driving force of the sodium/calcium exchanger, inhibiting calcium extrusion and possibly facilitating calcium entry. Additionally, Istaroxime increases intracellular calcium by improving the efficacy by which intracellular calcium triggers sarco...
T37767 Transdermal Peptide Disulfide TFA

Transdermal Peptide Disulfide TFA (TD 1 Disulfide(peptide) TFA), an 11-amino acid peptide, specifically binds to the Na+/K+-ATPase beta-subunit (ATP1B1), predominantly interacting with its C-terminus. This compound is capable of enhancing the transdermal delivery of various macromolecules[1].
T75360 Oxonol VI

Oxonol VI 是一种膜电位的光学指示剂,在脂质囊泡中发挥作用。它能用于监测重组囊泡中与 (Na++K+)-ATPase 活性相关的膜电位变化。
TP1032 Transdermal Peptide TFA (918629-48-8 free base)

Transdermal Peptide TFA,TD 1 (peptide) (TFA)

Transdermal Peptide TFA (TD 1 Peptide TFA) is an 11-amino acid polypeptide that binds to Na+/K+ -atpase beta-subunit (ATP1B1) and interacts with the C terminal of ATP1B1.Transdermal Peptide TFA can enhance the transmission of some large molecules in the s
T71122 Carsatrin (free base)

Carsatrin is purinylpiperazine derivative. as cardiotonic and antiarrhythmic. Carsatrin acts as positive inotropic agent that increases twitch tension and prolongs the action potential (AP) duration of ventricular muscle without affecting the Na+, K+-ATPase, adenylyl cyclase, phosphodiesterase isozymes, or cardiac myofilaments. Carsatrin’s positive inotropic effect can be prevented by tetrodotoxin but not by the adrenergic antagonists timolol, yohimbine, or prazosin
T70975 Carsatrin succinate

Carsatrin succinate is the salt form of Carsatin, a purinylpiperazine derivative used as a cardiotonic and antiarrhythmic. Carsatrin acts as positive inotropic agent that increases twitch tension and prolongs the action potential (AP) duration of ventricular muscle without affecting the Na+, K+-ATPase, adenylyl cyclase, phosphodiesterase isozymes, or cardiac myofilaments. Carsatrin’s positive inotropic effect can be prevented by tetrodotoxin but not by the adrenergic antagonists timolol, yohimbi...
T38151 Germicidin A

Germicidin A is a pyranone originally derived from S. viridochromogenes that acts as a reversible, autoregulative inhibitor of spore germination and hyphal elongation in the genus Streptomyces at concentrations as low as 200 pM. During germination, spores of Streptomyces excrete germicidin A along with other germicidin homologs, which inhibit germination of its own arthrospores. At higher concentrations, germicidin A can inhibit the porcine Na+/K+-activated ATPase (ID50 = 100 μM) and prevent the...
T68808 11-Dehydrocorticosterone

11-Dehydrocorticosterone is an endogenous mineralocorticoid. It increases Na+/K+-ATPase mRNA expression in vascular smooth muscle cells and inhibits aldosterone action in B. marinus toad bladder tissue in a concentration-dependent manner. 11-Dehydrocorticosterone decreases the sodium/creatine ratio and increases the potassium/creatine ratio in rat urine in a dose-dependent manner in a model of 11β-hydroxysteroid dehydrogenase inhibition induced by carbenoxolone. Chronic administration 11-dehydro...
T70428 Nepaprazole sodium

Nepaprazole Na is the salt form of Nepaprazole Free Base, also known as TY-11345, is a proton pump inhibitor potentially for treatment of gastric ulcer. TY-11345 potently inhibited H+/K(+)-ATPase activity in isolated rabbit gastric mucosal microsomes; and the inhibitory effect was enhanced under weak acid conditions, the IC50 (concentrations that inhibit the enzyme activity by 50%) being 5.8 microM and 9.9 microM at pH 6.0 and pH 7.4, respectively. TY-11345 should be useful for the clinical tre...
T36659 Boromycin

Boromycin is a boron-containing macrolide antibiotic that has been found in Streptomyces. Boromycin inhibits growth of B. subtilis (MIC = 0.05 μg/ml) and induces efflux of potassium ions from B. subtilis without affecting Na+/K+-ATPase activity. It decreases the synthesis of protein, RNA, and DNA in B. subtilis when used at a concentration of 0.05 μg/ml. It inhibits the growth of B. halodurans (MIC = 10 ng/ml) and inhibits the futalosine pathway of menaquinone synthesis in B. halodurans. Boromyc...

化合物

Suloctidil
Cat.No: T0712
Synonym:
Target: ATPase, Platelet aggregation
Chloroprocaine hydrochloride
Cat.No: T6443
Synonym: 盐酸氯普鲁卡因,Chloroprocaine HCl
Target: ATPase, Others
Chlorpropamide
Cat.No: T0490
Synonym: Diabinese,氯磺丙脲
Target: ATPase, ABC
Prilocaine
Cat.No: T6953
Synonym: Citanest,丙胺卡因,Propitocaine,NSC 40027
Target: ATPase, Sodium Channel
Prilocaine hydrochloride
Cat.No: T0796
Synonym: Prilocaine HCl,Propitocaine hydrochloride,Xylonest,盐酸丙胺卡因
Target: ATPase, Sodium Channel
2,3-Butanedione 2-Monoxime
Cat.No: T2176
Synonym: Diacetyl monoxime,2,3-Butanedione-2-monoxime
Target: Akt
Rostafuroxin
Cat.No: T2621
Synonym: PST 2238
Target: ATPase, RSV
Sodium orthovanadate
Cat.No: T2189
Synonym: Sodium vanadate,钒酸钠,Trisodium vanadate,Sodium pervanadate
Target: ATPase, Phosphatase
Farglitazar
Cat.No: T27303
Synonym: GI-262570,GI 262570,GI262570
Target:
5-IAF
Cat.No: T14052
Synonym: 5-Iodoacetamidofluorescein
Target:
Transdermal Peptide Disulfide Acetate
Cat.No: TP1033L
Synonym: TD 1 (peptide) acetate,Transdermal Peptide Disulfide Acetate (888486-23-5 free base)
Target: ATPase
Istaroxime
Cat.No: T15600
Synonym: PST2744
Target: Others
Istaroxime hydrochloride
Cat.No: T15599
Synonym: PST2744 hydrochloride
Target: Others
Digoxigenin Monodigitoxoside
Cat.No: T36060
Synonym:
Target:
ASI-254
Cat.No: T68916
Synonym:
Target:
SPAI-1
Cat.No: T76374
Synonym:
Target:
Caloxin 2A1 TFA
Cat.No: T35923
Synonym:
Target:
Prilocaine acetate
Cat.No: T75280
Synonym:
Target:
Depramine
Cat.No: T78564
Synonym: GP 31406
Target:
Tenellin
Cat.No: T71806
Synonym:
Target:
Caloxin 2A1
Cat.No: T40437
Synonym:
Target:
(R)-Tegoprazan
Cat.No: T72812
Synonym:
Target:
Chloroprocaine
Cat.No: T60469
Synonym:
Target:
14-Anhydrodigitoxigenin
Cat.No: T37707
Synonym:
Target:
Transdermal Peptide (TD 1 (peptide))
Cat.No: T37766
Synonym:
Target:
Istaroxime oxalate
Cat.No: T69975
Synonym:
Target:
Transdermal Peptide Disulfide TFA
Cat.No: T37767
Synonym:
Target:
Oxonol VI
Cat.No: T75360
Synonym:
Target:
Transdermal Peptide TFA (918629-48-8 free base)
Cat.No: TP1032
Synonym: Transdermal Peptide TFA,TD 1 (peptide) (TFA)
Target:
Carsatrin (free base)
Cat.No: T71122
Synonym:
Target:
Carsatrin succinate
Cat.No: T70975
Synonym:
Target:
Germicidin A
Cat.No: T38151
Synonym:
Target:
11-Dehydrocorticosterone
Cat.No: T68808
Synonym:
Target:
Nepaprazole sodium
Cat.No: T70428
Synonym:
Target:
Boromycin
Cat.No: T36659
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T1719 Bufalin

ATPase Membrane transporter/Ion channel
Bufalin 是蟾酥中的一种成分,是Na+/K+-ATPase 抑制剂,具有抗肿瘤活性,可与其基 α1、α2 和 α3 结合,Kd 值分别为 42.5、45 和 40 nM。
TJP2872 Acevaltrate

Acevaltratum,乙酰缬草三酯,Acetoxyvaltrate

ATPase; Others Membrane transporter/Ion channel; Others
Acevaltrate (Acevaltratum) 对人小细胞肺癌细胞系 GLC(4) 和人结肠直肠癌细胞系 COLO 320 具有高细胞毒性,IC50 值为 1-6 uM。它抑制大鼠肾和脑半球中 Na+/K+-ATP 酶活性,IC50分别为 22.8 和 42.3 μM。
T5S0890 Oleandrin

Neriostene,Folinerin,Foliandrin,欧夹竹桃苷

Apoptosis; ATPase; Potassium Channel; Sodium Channel Apoptosis; Membrane transporter/Ion channel
Oleandrin (Folinerin) 是夹竹桃属中的一种类固醇,可抑制Na+/K+-ATPase 活性,IC50为 620 nM。
TN5073 Strophanthidin

毒毛旋花子甙元,Strophanthidine,葡萄球菌素

ATPase; Calcium Channel Membrane transporter/Ion channel; Metabolism
Strophanthidin (Strophanthidine) 是黄花夹竹桃中的一种类固醇,可增加舒张期和收缩期胞内 Ca2+浓度。它在 0.1 和 1 nmol/L 增加Na+/K+-ATPase 活性,1到100 μ mol/L 抑制Na+/K+-ATPase 活性,10 和 100 nmol/L 对Na+/K+-ATPase 活性无影响。
T0295 Digitoxin

Digitoxoside,洋地黄毒苷,Unidigin,洋地黄毒甙,Digitoxinum,洋地黄

ATPase; Others Membrane transporter/Ion channel; Others
Digitoxin (Digitoxinum) 是Na+/K+-ATPase 有效抑制剂, EC50 值为0.78 μM。
T8183 Deslanoside

洋地黄,去乙酰西地兰,Desacetyllanatoside C,Deacetyllanatoside C

ATPase; Drug Metabolite Membrane transporter/Ion channel; Metabolism
Deslanoside (Desacetyllanatoside C) 是一种快速作用的强心苷,可抑制Na-K-ATPase 膜泵,导致细胞内钠和钙浓度增加。它用于研究充血性心力衰竭和因折返机制引起的室上性心律失常,并在研究慢性心房颤动时控制心室率。
T2922 Phlorizin

Floridzin,根皮甙,根皮苷,NSC 2833,Phloridzin

ATPase; SGLT GPCR/G Protein; Membrane transporter/Ion channel
Phlorizin (Phloridzin) 是非选择性的SGLT 抑制剂,也是Na+/K+-ATPase 抑制剂,对于hSGLT1和hSGLT2的Ki 值分别为 300 和 39 nM。
T2O2668 Oleic acid

Elaidoic acid,9Z-Octadecenoic acid,Oleate,9-Octadecenoic Acid,Glycon Wo,9-cis-Octadecenoic acid,油酸

Apoptosis; ATPase; Others; Endogenous Metabolite Apoptosis; Membrane transporter/Ion channel; Metabolism; Others
Oleic acid (Glycon Wo) 属于天然产物,是一种常见的饱和脂肪酸,在存在于多种动物、植物的脂肪和油脂中。Palmitic acid 是一种 Na+/K+ATP 酶激活剂。
T2822 Ginsenoside Rb1

Gypenoside Ⅲ,人参皂苷Rb1,人参皂苷 Rb1,Gypenoside III

ATPase; Mitophagy; IRAK; NF-κB; Autophagy; HSV Autophagy; Immunology/Inflammation; Membrane transporter/Ion channel; Microbiology/Virology; NF-κB
Ginsenoside Rb1 (Gypenoside Ⅲ) 是中药人参的成分,可能具有抑制或阻止肿瘤生长的特性。
T3432 Cinobufagin

华蟾蜍精,华蟾酥毒基,Cinobufagine

Apoptosis; ATPase; Autophagy Apoptosis; Autophagy; Membrane transporter/Ion channel
Cinobufagin (Cinobufagine) 是一种具有抗肿瘤功效的天然产物。
T36390 Sodium oleate

Oleic acid sodium salt,Sodium oleate,cis-9-Octadecenoic acid sodium salt

ATPase Membrane transporter/Ion channel
Sodium oleate (cis-9-Octadecenoic acid sodium salt) (Oleic acid sodium) 是人脂肪细胞和其他组织中最常见的单不饱和脂肪酸钠盐。Sodium oleate 是一种 Na+/K+ ATP 酶激活剂。
T4973 Paraxanthine

1,7-二甲基黄嘌呤,1,7-DIMETHYLXANTHINE

Endogenous Metabolite Metabolism
Paraxanthine (1,7-dimethylxanthine) 是一种 caffeine 的代谢物,能够刺激Ryanodine 受体通道来抑制多巴胺能细胞的死亡。
T6S1049 Wilforine

ATPase Membrane transporter/Ion channel
Wilforine 是一倍半萜吡啶化合物,T. wilfordii 植物中的重要生物活性化合物,可有效治疗特发性肺纤维化。它具有抗炎和杀虫活性。
T7190 Actein

Apoptosis; Akt; JNK; Autophagy Apoptosis; Autophagy; Cytoskeletal Signaling; MAPK; PI3K/Akt/mTOR signaling
Actein 是从升麻的根茎中分离的一种三萜糖苷,通过促进ROS/JNK 活化和钝化人膀胱癌中的AKT 途径来抑制细胞增殖,诱导自噬和凋亡。
T5S1982 Periplocin

Periplocoside,杠柳毒苷

Apoptosis; Others Apoptosis; Others
Periplocin (Periplocoside) 是从黑龙骨中分离出的一种强心类固醇。它可促进肿瘤细胞凋亡并抑制肿瘤生长。它通过激活 Na/K-ATPase 介导的 Src/ERK 和 PI3K/Akt 途径,具有促进伤口愈合的潜力。
T13618 Citreoviridin

Others Others
Citreoviridin, a toxin from Penicillium citreoviride NRRL 2579, inhibits brain synaptosomal Na+/K+-ATPase whereas, in microsomes, both Na+/K+-ATPase and Mg2+-ATPase activities are significantly stimulated in a dose-dependent manner.
TN6631 Chamigrenol

Chamigrenol is a promising candidate for the development of potent Na+/K+ ATPase inhibitors and antimicrobial agents. It inhibited the activities of Na+/K+-ATPase, with the IC50 value of 15.9 ± 0.54 μg/mL.
TN5141 Thevetin B

ATPase; Potassium Channel; Sodium Channel Membrane transporter/Ion channel
Thevetin B 是一种强心苷,是Na+-, K+-依赖性腺苷三磷酸酶 (Na+,K+-ATPase) 的抑制剂,来自 Thevetia peruviana
TN4697 Odoroside H

ATPase; Potassium Channel; Sodium Channel Membrane transporter/Ion channel
Odoroside H has anticancer activities, the cytotoxic effects are induced by the inhibition of the plasma membrane bound Na(+)/K(+)-ATPase.
TN2306 Wilfordine

ATPase; Potassium Channel; Sodium Channel Membrane transporter/Ion channel
Wilfordine is an insecticidally active alkaloid, Na+-K+-ATPase may be an acting target of wilfordine against some larvae of insect.
TN5060 Stauntosaponin A

ATPase; Potassium Channel; Sodium Channel Membrane transporter/Ion channel
Stauntosaponin A and stauntosaponin B show moderate inhibitory activities against Na+/K+-ATPase with IC50 values of 21 and 29 uM, respectively.
T38069 Aquastatin A

Aquastatin A is a fungal metabolite originally isolated fromF. aquaeductuumthat has diverse biological activities.1It is active againstS. aureus(MIC = 32 μg/ml) and inhibits enoyl-acyl carrier protein reductase (Fabl; IC50= 3.2 μM) andS. aureusfatty acid synthesis (IC50= 3.5 μM).2Aquastatin A also inhibits the Na+/K+-ATPase and H+/K+-ATPase (IC50s = 7.1 and 6.2 μM, respectively), as well as protein tyrosine phosphatase 1B (PTP1B; IC50= 0.19 μM).1,3 1.Hamano, K., Kinoshita-Okami, M., Minagawa, K....
T35779 Oosporein

Oosporein is a mycotoxin that has been found inBeauveriaand has diverse biological activities.1,2It is cytotoxic to Sf9 and Sf21 insect cells with 50% cytotoxic concentration (CC50) values of 4.23 and 10.43 μM, respectively.3Oosporin induces lethality in day-old cockerels (LD50= 6.12 mg/kg).4It inhibits Na+/K+-, Ca2+-, and Mg2+-ATPase activities by 27, 52, and 100%, respectively, in equine erythrocyte ghosts when used at a concentration of 200 μg/ml.2Oosporein inhibits herpes simplex 1 (HSV-1), ...

天然产物

Bufalin
Cat.No: T1719
Synonym:
Target: ATPase
Acevaltrate
Cat.No: TJP2872
Synonym: Acevaltratum,乙酰缬草三酯,Acetoxyvaltrate
Target: ATPase, Others
Oleandrin
Cat.No: T5S0890
Synonym: Neriostene,Folinerin,Foliandrin,欧夹竹桃苷
Target: Apoptosis, ATPase, Potassium Channel, Sodium Channel
Strophanthidin
Cat.No: TN5073
Synonym: 毒毛旋花子甙元,Strophanthidine,葡萄球菌素
Target: ATPase, Calcium Channel
Digitoxin
Cat.No: T0295
Synonym: Digitoxoside,洋地黄毒苷,Unidigin,洋地黄毒甙,Digitoxinum,洋地黄
Target: ATPase, Others
Deslanoside
Cat.No: T8183
Synonym: 洋地黄,去乙酰西地兰,Desacetyllanatoside C,Deacetyllanatoside C
Target: ATPase, Drug Metabolite
Phlorizin
Cat.No: T2922
Synonym: Floridzin,根皮甙,根皮苷,NSC 2833,Phloridzin
Target: ATPase, SGLT
Oleic acid
Cat.No: T2O2668
Synonym: Elaidoic acid,9Z-Octadecenoic acid,Oleate,9-Octadecenoic Acid,Glycon Wo,9-cis-Octadecenoic acid,油酸
Target: Apoptosis, ATPase, Others, Endogenous Metabolite
Ginsenoside Rb1
Cat.No: T2822
Synonym: Gypenoside Ⅲ,人参皂苷Rb1,人参皂苷 Rb1,Gypenoside III
Target: ATPase, Mitophagy, IRAK, NF-κB, Autophagy, HSV
Cinobufagin
Cat.No: T3432
Synonym: 华蟾蜍精,华蟾酥毒基,Cinobufagine
Target: Apoptosis, ATPase, Autophagy
Sodium oleate
Cat.No: T36390
Synonym: Oleic acid sodium salt,Sodium oleate,cis-9-Octadecenoic acid sodium salt
Target: ATPase
Paraxanthine
Cat.No: T4973
Synonym: 1,7-二甲基黄嘌呤,1,7-DIMETHYLXANTHINE
Target: Endogenous Metabolite
Wilforine
Cat.No: T6S1049
Synonym:
Target: ATPase
Actein
Cat.No: T7190
Synonym:
Target: Apoptosis, Akt, JNK, Autophagy
Periplocin
Cat.No: T5S1982
Synonym: Periplocoside,杠柳毒苷
Target: Apoptosis, Others
Citreoviridin
Cat.No: T13618
Synonym:
Target: Others
Chamigrenol
Cat.No: TN6631
Synonym:
Target:
Thevetin B
Cat.No: TN5141
Synonym:
Target: ATPase, Potassium Channel, Sodium Channel
Odoroside H
Cat.No: TN4697
Synonym:
Target: ATPase, Potassium Channel, Sodium Channel
Wilfordine
Cat.No: TN2306
Synonym:
Target: ATPase, Potassium Channel, Sodium Channel
Stauntosaponin A
Cat.No: TN5060
Synonym:
Target: ATPase, Potassium Channel, Sodium Channel
Aquastatin A
Cat.No: T38069
Synonym:
Target:
Oosporein
Cat.No: T35779
Synonym:
Target:
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